Rigas Labs

In 1978, W.C. Still introduced a modified version of column chromatography called flash column chromatography .The technique is very similar to the traditional column chromatography, except that the solvent is driven through the column by applying positive pressure. This method is used solely in organic teaching labs because of its ease and environmentally friendly nature. This allowed most separations to be performed in less than 20 minutes, with improved separations compared to the old method. Modern flash chromatography systems are sold as pre-packed plastic cartridges, and the solvent is pumped through the cartridge. Systems may also be linked with detectors and fraction collectors providing automation. The introduction of gradient pumps resulted in quicker separations and less solvent usage.