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The sensitivity, selectivity, flexibility, and ease-of-use provided by hybrid quadrupole-Orbitrap mass spectrometers set the standard for screening, quantitation, identification, and confirmation of targeted and untargeted compounds. The Thermo Scientific™ Q Exactive™ Focus hybrid quadrupole-Orbitrap MS makes this power accessible to environmental, food safety, clinical research, forensic toxicology, and pharmaceutical labs challenged by growing sample volumes and constrained by strict budgets. The Q Exactive Focus system simplifies method development, saving time and decreasing costs while reliably delivering unsurpassed results.

The Q Exactive Focus mass spectrometer brings the benefits of HRAM data, plus proven system reliability, to laboratories performing routine analyses ranging from targeted quantification to non-targeted screening. HRAM MS allows you to detect and quantify all precursor ions in a sample without the need for individual compound tuning and optimization as required with triple quadrupole based quantitation. The Q Exactive Focus MS system enables highly selective detection and quantitation of both targeted and non-targeted compounds in complex matrices with minimal method development, saving time and increasing lab productivity. 

Confident identification enabled by Orbitrap high resolution

The 70,000 resolution and 1 ppm mass accuracy performance of the Q Exactive Focus MS redefines the standard for accurate quantitation and identification by effectively resolving analytes from interferences in highly complex matrices.

Up to 6 orders of magnitude of linear dynamic range covers a wide range of concentrations

The Q Exactive Focus MS offers quantitative analyses at up to 6 orders of magnitude of linear quantitative dynamic range.

HRAM MS/MS for analytical confidence

The Q Exactive Focus system can perform data-dependent “top 3 MS/MS” to generate spectra confirming analyte identification. A new acquisition mode, Variable Data Independent Analysis (vDIA), wherein all precursor ions are fragmented, creates a digital data archive for detection and potential retrospective quantification of all compounds in a sample.

Q Exactive Focus Hybrid Quadrupole-Orbitrap Mass Spectrometer
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